| San Jose Earthquakes vs. Sporting Kansas City | 2-21-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| San Jose Earthquakes vs. Atlanta United FC | 2-28-2026 Saturday 4:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Philadelphia Union vs. San Jose Earthquakes | 3-7-2026 Saturday 7:30 PM | Subaru Park in Chester, PA | View Tickets |
| San Jose Earthquakes vs. Seattle Sounders FC | 3-15-2026 Sunday 4:00 PM | PayPal Park in San Jose, CA | View Tickets |
| Vancouver Whitecaps FC vs. San Jose Earthquakes | 3-21-2026 Saturday 7:30 PM | BC Place Stadium in Vancouver, Canada | View Tickets |
| San Jose Earthquakes vs. San Diego FC | 4-4-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Sporting Kansas City vs. San Jose Earthquakes | 4-11-2026 Saturday 7:30 PM | Children's Mercy Park in Kansas City, KS | View Tickets |
| Los Angeles FC vs. San Jose Earthquakes | 4-19-2026 Sunday 4:00 PM | BMO Stadium in Los Angeles, CA | View Tickets |
| San Jose Earthquakes vs. Austin FC | 4-22-2026 Wednesday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| St. Louis City SC vs. San Jose Earthquakes | 4-25-2026 Saturday 7:30 PM | Energizer Park in St. Louis, MO | View Tickets |
| Toronto FC vs. San Jose Earthquakes | 5-2-2026 Saturday TBD | BMO Field in Toronto, Canada | View Tickets |
| San Jose Earthquakes vs. Vancouver Whitecaps FC | 5-9-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Seattle Sounders FC vs. San Jose Earthquakes | 5-13-2026 Wednesday 6:30 PM | Lumen Field in Seattle, WA | View Tickets |
| San Jose Earthquakes vs. FC Dallas | 5-16-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Portland Timbers vs. San Jose Earthquakes | 5-23-2026 Saturday 6:30 PM | Providence Park in Portland, OR | View Tickets |
| San Jose Earthquakes vs. Orlando City SC | 7-22-2026 Wednesday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| FC Cincinnati vs. San Jose Earthquakes | 8-1-2026 Saturday 7:30 PM | TQL Stadium in Cincinnati, OH | View Tickets |
| San Jose Earthquakes vs. St. Louis City SC | 8-15-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| LA Galaxy vs. San Jose Earthquakes | 8-19-2026 Wednesday 7:30 PM | Dignity Health Sports Park - Stadium in Carson, CA | View Tickets |
| San Jose Earthquakes vs. Minnesota United FC | 8-22-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Houston Dynamo FC vs. San Jose Earthquakes | 8-29-2026 Saturday 7:30 PM | Shell Energy Stadium in Houston, TX | View Tickets |
| Austin FC vs. San Jose Earthquakes | 9-5-2026 Saturday 7:30 PM | Q2 Stadium in Austin, TX | View Tickets |
| San Diego FC vs. San Jose Earthquakes | 9-9-2026 Wednesday 7:30 PM | Snapdragon Stadium in San Diego, CA | View Tickets |
| San Jose Earthquakes vs. Houston Dynamo FC | 9-12-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| San Jose Earthquakes vs. Portland Timbers | 9-26-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| Colorado Rapids vs. San Jose Earthquakes | 10-10-2026 Saturday 7:30 PM | Dick's Sporting Goods Park in Commerce City, CO | View Tickets |
| Real Salt Lake vs. San Jose Earthquakes | 10-14-2026 Wednesday 7:30 PM | America First Field in Sandy, UT | View Tickets |
| San Jose Earthquakes vs. Nashville SC | 10-17-2026 Saturday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| FC Dallas vs. San Jose Earthquakes | 10-24-2026 Saturday 7:30 PM | Toyota Stadium in Frisco, TX | View Tickets |
| San Jose Earthquakes vs. Colorado Rapids | 10-28-2026 Wednesday 7:30 PM | PayPal Park in San Jose, CA | View Tickets |
| San Jose Earthquakes vs. Real Salt Lake | 10-31-2026 Saturday TBD | PayPal Park in San Jose, CA | View Tickets |
| Minnesota United FC vs. San Jose Earthquakes | 11-7-2026 Saturday 6:00 PM | Allianz Field in Saint Paul, MN | View Tickets |