| Kentucky Wesleyan Panthers Football vs. West Florida Argonauts | 9-6-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
| William Jewell Cardinals Football vs. Kentucky Wesleyan Panthers | 9-13-2025
Saturday
6:00 PM | Greene Stadium in Liberty, MO | View Tickets |
| Kentucky Wesleyan Panthers Football vs. Walsh Cavaliers | 9-20-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
| Hillsdale College Chargers Football vs. Kentucky Wesleyan Panthers | 9-27-2025
Saturday
2:00 PM | Frank Waters Stadium in Hillsdale, MI | View Tickets |
| Kentucky Wesleyan Panthers Football vs. Ashland University Eagles | 10-4-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
| Kentucky Wesleyan Panthers Football vs. Ohio Dominican Panthers | 10-11-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
| Findlay Oilers Football vs. Kentucky Wesleyan Panthers | 10-18-2025
Saturday
TBD | Donnell Stadium in Findlay, OH | View Tickets |
| Kentucky Wesleyan Panthers Football vs. Northwood Timberwolves | 10-25-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
| Tiffin Dragons Football vs. Kentucky Wesleyan Panthers | 11-1-2025
Saturday
1:00 PM | Frost Kalnow Stadium in Tiffin, OH | View Tickets |
| Lake Erie Storm Football vs. Kentucky Wesleyan Panthers | 11-8-2025
Saturday
12:00 PM | Jack Britt Memorial Stadium in Painesville, OH | View Tickets |
| Kentucky Wesleyan Panthers Football vs. Thomas More Saints | 11-15-2025
Saturday
TBD | Steele Stadium in Owensboro, KY | View Tickets |
