| Missouri Southern State Lions Football vs. Midwestern State Mustangs | 8-30-2025
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Midwestern State Mustangs Football vs. Western Colorado Mountaineers | 9-6-2025
Saturday
TBD | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
| Midwestern State Mustangs Football vs. Eastern New Mexico Greyhounds | 9-20-2025
Saturday
TBD | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
| UT-Permian Basin Falcons Football vs. Midwestern State Mustangs | 9-27-2025
Saturday
6:00 PM | Astound Broadband Stadium in Midland, TX | View Tickets |
| Midwestern State Mustangs Football vs. Texas A&M-Kingsville Javelinas | 10-4-2025
Saturday
TBD | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
| Sul Ross State Lobos Football vs. Midwestern State Mustangs | 10-11-2025
Saturday
7:00 PM | Jackson Field - TX in Alpine, TX | View Tickets |
| Angelo State Rams Football vs. Midwestern State Mustangs | 10-18-2025
Saturday
TBD | LeGrand Stadium at 1st Community Credit Union Field in San Angelo, TX | View Tickets |
| Midwestern State Mustangs Football vs. Central Washington Wildcats | 10-25-2025
Saturday
TBD | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
| Western Oregon Wolves Football vs. Midwestern State Mustangs | 11-1-2025
Saturday
1:05 PM | McArthur Field in Monmouth, OR | View Tickets |
| Midwestern State Mustangs Football vs. West Texas A&M Buffaloes | 11-8-2025
Saturday
TBD | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
